The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIM2-20-RE | 20 (40 μL) | 200 μL |  |
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| TRIM2-20-OR | 20 (40 μL) | 200 μL |  |
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| TRIM2-20-GO | 20 (40 μL) | 200 μL |  |
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| TRIM2-20-GR | 20 (40 μL) | 200 μL |  |
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| TRIM2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Symbol : TRIM2
Gene Name : Tripartite motif containing 2
Chromosome : CHR 4: 153,152,280-153,339,321
Locus : 4q31.3
Alt. Genes : KIF20A
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