The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIM22-20-RE | 20 (40 μL) | 200 μL |  |
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| TRIM22-20-OR | 20 (40 μL) | 200 μL |  |
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| TRIM22-20-GO | 20 (40 μL) | 200 μL |  |
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| TRIM22-20-GR | 20 (40 μL) | 200 μL |  |
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| TRIM22-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
Gene Symbol : TRIM22
Gene Name : Tripartite motif containing 22
Chromosome : CHR 11: 568,958,6-571,086,2
Locus : 11p15.4
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