This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRPM1-20-RE | 20 (40 μL) | 200 μL |  |
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| TRPM1-20-OR | 20 (40 μL) | 200 μL |  |
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| TRPM1-20-GO | 20 (40 μL) | 200 μL |  |
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| TRPM1-20-GR | 20 (40 μL) | 200 μL |  |
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| TRPM1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Symbol : TRPM1
Gene Name : Transient receptor potential cation channel subfamily M member 1
Chromosome : CHR 15: 311,612,72-310,010,60
Locus : 15q13.3
Alt. Genes : AKAP9
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