This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRPM7-20-RE | 20 (40 μL) | 200 μL |  |
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| TRPM7-20-OR | 20 (40 μL) | 200 μL |  |
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| TRPM7-20-GO | 20 (40 μL) | 200 μL |  |
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| TRPM7-20-GR | 20 (40 μL) | 200 μL |  |
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| TRPM7-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
Gene Symbol : TRPM7
Gene Name : Transient receptor potential cation channel subfamily M member 7
Chromosome : CHR 15: 506,868,34-505,571,57
Locus : 15q21.2
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