This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRRAP-20-RE | 20 (40 μL) | 200 μL |  |
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| TRRAP-20-OR | 20 (40 μL) | 200 μL |  |
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| TRRAP-20-GO | 20 (40 μL) | 200 μL |  |
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| TRRAP-20-GR | 20 (40 μL) | 200 μL |  |
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| TRRAP-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Symbol : TRRAP
Gene Name : Transformation/transcription domain associated protein
Chromosome : CHR 7: 988,784,89-990,132,42
Locus : 7q22.1
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