This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TSC22D1-20-RE | 20 (40 μL) | 200 μL |  |
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| TSC22D1-20-OR | 20 (40 μL) | 200 μL |  |
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| TSC22D1-20-GO | 20 (40 μL) | 200 μL |  |
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| TSC22D1-20-GR | 20 (40 μL) | 200 μL |  |
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| TSC22D1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Gene Symbol : TSC22D1
Gene Name : TSC22 domain family member 1
Chromosome : CHR 13: 445,765,64-444,321,42
Locus : 13q14.11
Alt. Genes : CEBPZ
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