TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TTL-20-RE | 20 (40 μL) | 200 μL |  |
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| TTL-20-OR | 20 (40 μL) | 200 μL |  |
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| TTL-20-GO | 20 (40 μL) | 200 μL |  |
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| TTL-20-GR | 20 (40 μL) | 200 μL |  |
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| TTL-20-AQ | 20 (40 μL) | 200 μL |  |
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TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008]
Gene Symbol : TTL
Gene Name : Tubulin tyrosine ligase
Chromosome : CHR 2: 112,482,126-112,532,645
Locus : 2q14.1
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