This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TULP3-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TULP3-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TULP3-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TULP3-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TULP3-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]
Gene Symbol : TULP3
Gene Name : Tubby like protein 3
Chromosome : CHR 12: 289,086,6-294,113,9
Locus : 12p13.33
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.