This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. [provided by RefSeq, Oct 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TUSC3-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
TUSC3-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
TUSC3-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
TUSC3-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
TUSC3-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. [provided by RefSeq, Oct 2017]
Gene Symbol : TUSC3
Gene Name : Tumor suppressor candidate 3
Chromosome : CHR 8: 155,400,86-157,666,48
Locus : 8p22
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