This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TXNDC12-20-RE | 20 (40 μL) | 200 μL |  |
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| TXNDC12-20-OR | 20 (40 μL) | 200 μL |  |
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| TXNDC12-20-GO | 20 (40 μL) | 200 μL |  |
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| TXNDC12-20-GR | 20 (40 μL) | 200 μL |  |
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| TXNDC12-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
Gene Symbol : TXNDC12
Gene Name : Thioredoxin domain containing 12
Chromosome : CHR 1: 520,561,70-520,201,30
Locus : 1p32.3
Alt. Genes : LRPPRC
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