The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2D3-20-RE | 20 (40 μL) | 200 μL |  |
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| UBE2D3-20-OR | 20 (40 μL) | 200 μL |  |
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| UBE2D3-20-GO | 20 (40 μL) | 200 μL |  |
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| UBE2D3-20-GR | 20 (40 μL) | 200 μL |  |
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| UBE2D3-20-AQ | 20 (40 μL) | 200 μL |  |
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. [provided by RefSeq, Jan 2017]
Gene Symbol : UBE2D3
Gene Name : Ubiquitin conjugating enzyme E2 D3
Chromosome : CHR 4: 102,868,892-102,794,382
Locus : 4q24
Alt. Genes : RASA4
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