The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2K-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| UBE2K-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| UBE2K-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| UBE2K-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| UBE2K-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : UBE2K
Gene Name : Ubiquitin conjugating enzyme E2 K
Chromosome : CHR 4: 396,980,43-397,827,91
Locus : 4p14
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.