Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2R2-20-RE | 20 (40 μL) | 200 μL |  |
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| UBE2R2-20-OR | 20 (40 μL) | 200 μL |  |
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| UBE2R2-20-GO | 20 (40 μL) | 200 μL |  |
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| UBE2R2-20-GR | 20 (40 μL) | 200 μL |  |
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| UBE2R2-20-AQ | 20 (40 μL) | 200 μL |  |
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Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
Gene Symbol : UBE2R2
Gene Name : Ubiquitin conjugating enzyme E2 R2
Chromosome : CHR 9: 338,171,63-339,204,02
Locus : 9p13.3
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