Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBN1-20-RE | 20 (40 μL) | 200 μL |  |
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| UBN1-20-OR | 20 (40 μL) | 200 μL |  |
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| UBN1-20-GO | 20 (40 μL) | 200 μL |  |
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| UBN1-20-GR | 20 (40 μL) | 200 μL |  |
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| UBN1-20-AQ | 20 (40 μL) | 200 μL |  |
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Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]
Gene Symbol : UBN1
Gene Name : Ubinuclein 1
Chromosome : CHR 16: 484,666,4-488,240,0
Locus : 16p13.3
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