This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UCMA-20-RE | 20 (40 μL) | 200 μL |  |
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| UCMA-20-OR | 20 (40 μL) | 200 μL |  |
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| UCMA-20-GO | 20 (40 μL) | 200 μL |  |
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| UCMA-20-GR | 20 (40 μL) | 200 μL |  |
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| UCMA-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
Gene Symbol : UCMA
Gene Name : Upper zone of growth plate and cartilage matrix associated
Chromosome : CHR 10: 132,343,27-132,217,65
Locus : 10p13
Alt. Genes : G3BP1
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