The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ULBP1-20-RE | 20 (40 μL) | 200 μL |  |
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| ULBP1-20-OR | 20 (40 μL) | 200 μL |  |
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| ULBP1-20-GO | 20 (40 μL) | 200 μL |  |
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| ULBP1-20-GR | 20 (40 μL) | 200 μL |  |
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| ULBP1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Symbol : ULBP1
Gene Name : UL16 binding protein 1
Chromosome : CHR 6: 149,963,973-149,973,714
Locus : 6q25.1
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