This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UNC5B-20-RE | 20 (40 μL) | 200 μL |  |
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| UNC5B-20-OR | 20 (40 μL) | 200 μL |  |
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| UNC5B-20-GO | 20 (40 μL) | 200 μL |  |
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| UNC5B-20-GR | 20 (40 μL) | 200 μL |  |
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| UNC5B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Symbol : UNC5B
Gene Name : Unc-5 netrin receptor B
Chromosome : CHR 10: 712,125,34-713,028,78
Locus : 10q22.1
Alt. Genes : FEM1B
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