This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP15-20-RE | 20 (40 μL) | 200 μL |  |
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| USP15-20-OR | 20 (40 μL) | 200 μL |  |
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| USP15-20-GO | 20 (40 μL) | 200 μL |  |
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| USP15-20-GR | 20 (40 μL) | 200 μL |  |
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| USP15-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]
Gene Symbol : USP15
Gene Name : Ubiquitin specific peptidase 15
Chromosome : CHR 12: 622,603,39-624,097,20
Locus : 12q14.1
Alt. Genes : KIF20A
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