This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP27X-20-RE | 20 (40 μL) | 200 μL |  |
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| USP27X-20-OR | 20 (40 μL) | 200 μL |  |
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| USP27X-20-GO | 20 (40 μL) | 200 μL |  |
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| USP27X-20-GR | 20 (40 μL) | 200 μL |  |
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| USP27X-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability. [provided by RefSeq, Dec 2016]
Gene Symbol : USP27X
Gene Name : Ubiquitin specific peptidase 27, X-linked
Chromosome : CHR X: 498,798,66-498,825,64
Locus : Xp11.23
Alt. Genes : ATP6AP2
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