This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of this gene is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP35-20-RE | 20 (40 μL) | 200 μL |  |
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| USP35-20-OR | 20 (40 μL) | 200 μL |  |
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| USP35-20-GO | 20 (40 μL) | 200 μL |  |
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| USP35-20-GR | 20 (40 μL) | 200 μL |  |
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| USP35-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the peptidase C19 family of ubiquitin-specific proteases. These deubiquitinating enzymes (DUBs) catalyze the removal of ubiquitin proteins from other proteins. The encoded protein associates with polarized mitochondria and has been shown to inhibit NF-kappa B activation and delay PARK2-mediated degradation of mitochondria. Expression of this gene is upregulated by the let-7a microRNA and reduced expression has been observed in human tumor tissues. [provided by RefSeq, Jul 2017]
Gene Symbol : USP35
Gene Name : Ubiquitin specific peptidase 35
Chromosome : CHR 11: 781,888,11-782,336,50
Locus : 11q14.1
Alt. Genes : FAM13A
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