Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VCL-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| VCL-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| VCL-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| VCL-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| VCL-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : VCL
Gene Name : Vinculin
Chromosome : CHR 10: 739,981,13-741,201,59
Locus : 10q22.2
Alt. Genes : LRPPRC
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.