The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VPREB1-20-RE | 20 (40 μL) | 200 μL |  |
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| VPREB1-20-OR | 20 (40 μL) | 200 μL |  |
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| VPREB1-20-GO | 20 (40 μL) | 200 μL |  |
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| VPREB1-20-GR | 20 (40 μL) | 200 μL |  |
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| VPREB1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Symbol : VPREB1
Gene Name : V-set pre-B cell surrogate light chain 1
Chromosome : CHR 22: 222,447,79-222,455,14
Locus : 22q11.22
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