Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VPS11-20-RE | 20 (40 μL) | 200 μL |  |
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| VPS11-20-OR | 20 (40 μL) | 200 μL |  |
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| VPS11-20-GO | 20 (40 μL) | 200 μL |  |
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| VPS11-20-GR | 20 (40 μL) | 200 μL |  |
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| VPS11-20-AQ | 20 (40 μL) | 200 μL |  |
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Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Symbol : VPS11
Gene Name : VPS11, CORVET/HOPS core subunit
Chromosome : CHR 11: 119,067,751-119,081,977
Locus : 11q23.3
Alt. Genes : PREB
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