This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VPS35-20-RE | 20 (40 μL) | 200 μL |  |
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| VPS35-20-OR | 20 (40 μL) | 200 μL |  |
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| VPS35-20-GO | 20 (40 μL) | 200 μL |  |
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| VPS35-20-GR | 20 (40 μL) | 200 μL |  |
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| VPS35-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]
Gene Symbol : VPS35
Gene Name : VPS35, retromer complex component
Chromosome : CHR 16: 466,892,31-466,579,78
Locus : 16q11.2
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