The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
VTI1A-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
VTI1A-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
VTI1A-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
VTI1A-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
VTI1A-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Symbol : VTI1A
Gene Name : Vesicle transport through interaction with t-SNAREs 1A
Chromosome : CHR 10: 112,446,987-112,947,203
Locus : 10q25.2
Alt. Genes : HIPK3
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