This gene produces an RNA polymerase III transcript that resembles both a component of the ribonucleoprotein vault particle and a pre-microRNA. However, the RNA product does not function as a vault or microRNA; rather, it acts as a direct inhibitor of protein kinase R (also known as eukaryotic translation initiation factor 2-alpha kinase 2, EIF2AK2), and thereby plays an important role in the regulation of cell growth. This gene is located in the vicinity of a differentially methylated region (DMR) and is imprinted and may show allele-specific expression. This gene is also often hypermethylated and repressed in cancers. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VTRNA2-1-20-RE | 20 (40 μL) | 200 μL |  |
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| VTRNA2-1-20-OR | 20 (40 μL) | 200 μL |  |
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| VTRNA2-1-20-GO | 20 (40 μL) | 200 μL |  |
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| VTRNA2-1-20-GR | 20 (40 μL) | 200 μL |  |
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| VTRNA2-1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene produces an RNA polymerase III transcript that resembles both a component of the ribonucleoprotein vault particle and a pre-microRNA. However, the RNA product does not function as a vault or microRNA; rather, it acts as a direct inhibitor of protein kinase R (also known as eukaryotic translation initiation factor 2-alpha kinase 2, EIF2AK2), and thereby plays an important role in the regulation of cell growth. This gene is located in the vicinity of a differentially methylated region (DMR) and is imprinted and may show allele-specific expression. This gene is also often hypermethylated and repressed in cancers. [provided by RefSeq, Nov 2015]
Gene Symbol : VTRNA2-1
Gene Name : Vault RNA 2-1
Chromosome : CHR 5: 136,080,597-136,080,490
Locus : 5q31.1
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