This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
WASF2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
WASF2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
WASF2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
WASF2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
WASF2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Symbol : WASF2
Gene Name : WAS protein family member 2
Chromosome : CHR 1: 274,901,86-274,042,25
Locus : 1p36.11
Alt. Genes : ENAM
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