This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese. [provided by RefSeq, Nov 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
WDR13-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
WDR13-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
WDR13-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
WDR13-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
WDR13-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese. [provided by RefSeq, Nov 2016]
Gene Symbol : WDR13
Gene Name : WD repeat domain 13
Chromosome : CHR X: 485,974,91-486,051,93
Locus : Xp11.23
Alt. Genes : LRPPRC
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