This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WDR45-20-RE | 20 (40 μL) | 200 μL |  |
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| WDR45-20-OR | 20 (40 μL) | 200 μL |  |
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| WDR45-20-GO | 20 (40 μL) | 200 μL |  |
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| WDR45-20-GR | 20 (40 μL) | 200 μL |  |
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| WDR45-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : WDR45
Gene Name : WD repeat domain 45
Chromosome : CHR X: 491,011,20-490,744,32
Locus : Xp11.23
Alt. Genes : OPTN
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