This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
WDR83-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
WDR83-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
WDR83-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
WDR83-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
WDR83-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : WDR83
Gene Name : WD repeat domain 83
Chromosome : CHR 19: 126,668,03-126,758,31
Locus : 19p13.13
Alt. Genes : CELA3A
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