This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
WFDC8-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
WFDC8-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
WFDC8-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
WFDC8-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
WFDC8-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]
Gene Symbol : WFDC8
Gene Name : WAP four-disulfide core domain 8
Chromosome : CHR 20: 455,793,25-455,511,51
Locus : 20q13.12
Alt. Genes : ALG3
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