This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WNK4-20-RE | 20 (40 μL) | 200 μL |  |
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| WNK4-20-OR | 20 (40 μL) | 200 μL |  |
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| WNK4-20-GO | 20 (40 μL) | 200 μL |  |
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| WNK4-20-GR | 20 (40 μL) | 200 μL |  |
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| WNK4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009]
Gene Symbol : WNK4
Gene Name : WNK lysine deficient protein kinase 4
Chromosome : CHR 17: 427,797,00-427,970,65
Locus : 17q21.2
Alt. Genes : FEM1B
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