WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WWP1-20-RE | 20 (40 μL) | 200 μL |  |
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| WWP1-20-OR | 20 (40 μL) | 200 μL |  |
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| WWP1-20-GO | 20 (40 μL) | 200 μL |  |
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| WWP1-20-GR | 20 (40 μL) | 200 μL |  |
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| WWP1-20-AQ | 20 (40 μL) | 200 μL |  |
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WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008]
Gene Symbol : WWP1
Gene Name : WW domain containing E3 ubiquitin protein ligase 1
Chromosome : CHR 8: 863,427,10-864,683,56
Locus : 8q21.3
Alt. Genes : FEM1B
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