The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XCR1-20-RE | 20 (40 μL) | 200 μL |  |
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| XCR1-20-OR | 20 (40 μL) | 200 μL |  |
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| XCR1-20-GO | 20 (40 μL) | 200 μL |  |
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| XCR1-20-GR | 20 (40 μL) | 200 μL |  |
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| XCR1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : XCR1
Gene Name : X-C motif chemokine receptor 1
Chromosome : CHR 3: 460,868,02-460,169,89
Locus : 3p21.31
Alt. Genes : LINC01587
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