This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XPA-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| XPA-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| XPA-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| XPA-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| XPA-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
Gene Symbol : XPA
Gene Name : XPA, DNA damage recognition and repair factor
Chromosome : CHR 9: 976,974,08-976,543,97
Locus : 9q22.33
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.