The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XRCC1-20-RE | 20 (40 μL) | 200 μL |  |
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| XRCC1-20-OR | 20 (40 μL) | 200 μL |  |
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| XRCC1-20-GO | 20 (40 μL) | 200 μL |  |
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| XRCC1-20-GR | 20 (40 μL) | 200 μL |  |
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| XRCC1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Gene Symbol : XRCC1
Gene Name : X-ray repair cross complementing 1
Chromosome : CHR 19: 435,755,77-435,433,11
Locus : 19q13.31
Alt. Genes : OPTN
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