This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XRCC3-20-RE | 20 (40 μL) | 200 μL |  |
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| XRCC3-20-OR | 20 (40 μL) | 200 μL |  |
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| XRCC3-20-GO | 20 (40 μL) | 200 μL |  |
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| XRCC3-20-GR | 20 (40 μL) | 200 μL |  |
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| XRCC3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : XRCC3
Gene Name : X-ray repair cross complementing 3
Chromosome : CHR 14: 103,715,485-103,697,610
Locus : 14q32.33
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