This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| YWHAZ-20-RE | 20 (40 μL) | 200 μL |  |
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| YWHAZ-20-OR | 20 (40 μL) | 200 μL |  |
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| YWHAZ-20-GO | 20 (40 μL) | 200 μL |  |
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| YWHAZ-20-GR | 20 (40 μL) | 200 μL |  |
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| YWHAZ-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]
Gene Symbol : YWHAZ
Gene Name : Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
Chromosome : CHR 8: 100,954,067-100,918,575
Locus : 8q22.3
Alt. Genes : AKAP9
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