This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZBTB7B-20-RE | 20 (40 μL) | 200 μL |  |
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| ZBTB7B-20-OR | 20 (40 μL) | 200 μL |  |
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| ZBTB7B-20-GO | 20 (40 μL) | 200 μL |  |
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| ZBTB7B-20-GR | 20 (40 μL) | 200 μL |  |
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| ZBTB7B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Symbol : ZBTB7B
Gene Name : Zinc finger and BTB domain containing 7B
Chromosome : CHR 1: 155,002,627-155,018,524
Locus : 1q21.3
Alt. Genes : CEBPZ
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