This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ZMIZ1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ZMIZ1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ZMIZ1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ZMIZ1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ZMIZ1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Gene Symbol : ZMIZ1
Gene Name : Zinc finger MIZ-type containing 1
Chromosome : CHR 10: 790,689,93-793,165,27
Locus : 10q22.3
Alt. Genes : ZNF263
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