This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZMPSTE24-20-RE | 20 (40 μL) | 200 μL |  |
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| ZMPSTE24-20-OR | 20 (40 μL) | 200 μL |  |
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| ZMPSTE24-20-GO | 20 (40 μL) | 200 μL |  |
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| ZMPSTE24-20-GR | 20 (40 μL) | 200 μL |  |
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| ZMPSTE24-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
Gene Symbol : ZMPSTE24
Gene Name : Zinc metallopeptidase STE24
Chromosome : CHR 1: 402,580,49-402,941,83
Locus : 1p34.2
Alt. Genes : LRPPRC
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