The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF280B-20-RE | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-OR | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-GO | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-GR | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
Gene Symbol : ZNF280B
Gene Name : Zinc finger protein 280B
Chromosome : CHR 22: 225,091,86-224,844,20
Locus : 22q11.22
Alt. Genes : LRRC23
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