The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF346-20-RE | 20 (40 μL) | 200 μL |  |
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| ZNF346-20-OR | 20 (40 μL) | 200 μL |  |
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| ZNF346-20-GO | 20 (40 μL) | 200 μL |  |
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| ZNF346-20-GR | 20 (40 μL) | 200 μL |  |
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| ZNF346-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Symbol : ZNF346
Gene Name : Zinc finger protein 346
Chromosome : CHR 5: 177,022,679-177,081,188
Locus : 5q35.2
Alt. Genes : LRPPRC
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