Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF426-20-RE | 20 (40 μL) | 200 μL |  |
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| ZNF426-20-OR | 20 (40 μL) | 200 μL |  |
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| ZNF426-20-GO | 20 (40 μL) | 200 μL |  |
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| ZNF426-20-GR | 20 (40 μL) | 200 μL |  |
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| ZNF426-20-AQ | 20 (40 μL) | 200 μL |  |
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Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Symbol : ZNF426
Gene Name : Zinc finger protein 426
Chromosome : CHR 19: 953,867,2-952,322,3
Locus : 19p13.2
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