This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP2M1BA-20-REGO | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-REGR | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-GROR | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| AP2M1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Gene Symbol : AP2M1
Gene Name : Adaptor related protein complex 2 mu 1 subunit
Chromosome : CHR 3: 184,174,845-184,184,090
Locus : 3q27.1
Alt. Genes : HIPK3
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