This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APLP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| APLP1BA-20-REGR | 20 (40 μL) | 200 μL |
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| APLP1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| APLP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| APLP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| APLP1BA-20-GROR | 20 (40 μL) | 200 μL |
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| APLP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| APLP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : APLP1
Gene Name : Amyloid beta precursor like protein 1
Chromosome : CHR 19: 358,684,44-358,797,96
Locus : 19q13.12
Alt. Genes : AKAP9
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