APOC3 Break Apart FISH Probe

This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
APOC3BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
APOC3BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017]

Gene Details

Gene Symbol : APOC3

Gene Name : Apolipoprotein C3

Chromosome : CHR 11: 116,829,907-116,833,070

Locus : 11q23.3

Alt. Genes : SLC25A15

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