This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGDIABA-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-ORGR | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGDIABA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Symbol : ARHGDIA
Gene Name : Rho GDP dissociation inhibitor alpha
Chromosome : CHR 17: 818,714,05-818,677,18
Locus : 17q25.3
Alt. Genes : TRIM28
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