The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARL1BA-20-REGO | 20 (40 μL) | 200 μL |
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| ARL1BA-20-REGR | 20 (40 μL) | 200 μL |
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| ARL1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ARL1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ARL1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ARL1BA-20-GROR | 20 (40 μL) | 200 μL |
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| ARL1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ARL1BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Symbol : ARL1
Gene Name : ADP ribosylation factor like GTPase 1
Chromosome : CHR 12: 101,407,819-101,393,119
Locus : 12q23.2
Alt. Genes : OPTN
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