This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASCL1BA-20-REGO | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-REGR | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-GROR | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ASCL1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
Gene Symbol : ASCL1
Gene Name : Achaete-scute family bHLH transcription factor 1
Chromosome : CHR 12: 102,957,673-102,960,515
Locus : 12q23.2
Alt. Genes : CELA3A
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